A modeling approach to evaluate long-term outcome of prophylactic and on demand treatment strategies for severe hemophilia A

Background Severe hemophilia requires life-long treatment with expensive clotting factor concentrates; studies comparing effects of different therapeutic strategies over decades are very difficult to perform. A simulation model was developed to evaluate the long-term outcome of on demand, prophylact...

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Bibliographic Details
Main Authors: Kathelijn Fischer, Maurice E. Pouw, Daniel Lewandowski, Mart P. Janssen, H. Marijke van den Berg, Ben A. van Hout
Format: Article
Language:English
Published: Ferrata Storti Foundation 2011-05-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/5970