The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells

The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells

The precise control of growth and maintenance of the retinal ganglion cell (RGC) dendrite arborization is critical for normal visual functions in mammals. However, the underlying mechanisms remain elusive. Here, we find that the N6-methyladenosine (m6A) reader YTHDF2 is highly expressed in the mouse...

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Bibliographic Details
Main Authors: Fugui Niu, Peng Han, Jian Zhang, Yuanchu She, Lixin Yang, Jun Yu, Mengru Zhuang, Kezhen Tang, Yuwei Shi, Baisheng Yang, Chunqiao Liu, Bo Peng, Sheng-Jian Ji
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-02-01
Series:eLife
Subjects:
m6A modification
YTHDF2
retinal ganglion cell
dendrite
glaucoma
Online Access:https://elifesciences.org/articles/75827

Internet

https://elifesciences.org/articles/75827

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