Mechanism of μ-conotoxin PIIIA binding to the voltage-gated Na+ channel NaV1.4.
Several subtypes of voltage-gated Na+ (NaV) channels are important targets for pain management. μ-Conotoxins isolated from venoms of cone snails are potent and specific blockers of different NaV channel isoforms. The inhibitory effect of μ-conotoxins on NaV channels has been examined extensively, bu...
| Váldodahkkit: | , , |
|---|---|
| Materiálatiipa: | Artihkal |
| Giella: | English |
| Almmustuhtton: |
Public Library of Science (PLoS)
2014-01-01
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| Ráidu: | PLoS ONE |
| Liŋkkat: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0093267&type=printable |