Hyperferritinaemia in dengue virus infected patients is associated with immune activation and coagulation disturbances.

During a dengue outbreak on the Caribbean island Aruba, highly elevated levels of ferritin were detected in dengue virus infected patients. Ferritin is an acute-phase reactant and hyperferritinaemia is a hallmark of diseases caused by extensive immune activation, such as haemophagocytic lymphohistio...

Full description

Bibliographic Details
Main Authors: Cornelia A M van de Weg, Ralph M H G Huits, Cláudio S Pannuti, Rosalba M Brouns, Riemsdijk W A van den Berg, Henk-Jan van den Ham, Byron E E Martina, Albert D M E Osterhaus, Mihai G Netea, Joost C M Meijers, Eric C M van Gorp, Esper G Kallas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4191960?pdf=render