Somatic mutation detection and KRAS amplification in testicular germ cell tumors

Somatic mutation detection and KRAS amplification in testicular germ cell tumors

BackgroundTesticular Germ Cell Tumors (TGCT) are the most common cancer among young adult men. The TGCT histopathology is diverse, and the frequency of genomic alterations, along with their prognostic role, remains largely unexplored. Herein, we evaluate the mutation profile of a 15-driver gene pane...

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Prif Awduron: Eduardo R. M. Cabral, Marilia F. Pacanhella, Andre V. H. Lengert, Mariana B. dos Reis, Leticia F. Leal, Marcos A. de Lima, Aline L. V. da Silva, Icaro A. Pinto, Rui M. Reis, Mariana T. Pinto, Flavio M. Cárcano
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Frontiers Media S.A. 2023-03-01
Cyfres:Frontiers in Oncology
Pynciau:
testicular neoplasms
mutation
testicular germ cell tumor
K-ras Gene
TP53 Gene
next-generation sequencing
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fonc.2023.1133363/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1133363/full

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