Suppression of dual specificity phosphatase I expression inhibits hepatitis C virus replication.

It was reported that dual specificity phosphatase 1 (DUSP1) is specifically upregulated in the liver of patients with chronic hetpatitis C virus (HCV) infection who do not respond to peginterferon (PegIFN) treatment. Here, we have investigated the role of DUSP1 in HCV replication in hepatoma cells s...

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Bibliographic Details
Main Authors: Jung Eun Choi, Jung Hyun Kwon, Jung-Hee Kim, Wonhee Hur, Pil Soo Sung, Sang Wook Choi, Seung Kew Yoon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4370512?pdf=render