Suppression of dual specificity phosphatase I expression inhibits hepatitis C virus replication.

Suppression of dual specificity phosphatase I expression inhibits hepatitis C virus replication.

It was reported that dual specificity phosphatase 1 (DUSP1) is specifically upregulated in the liver of patients with chronic hetpatitis C virus (HCV) infection who do not respond to peginterferon (PegIFN) treatment. Here, we have investigated the role of DUSP1 in HCV replication in hepatoma cells s...

Full description

Bibliographic Details
Main Authors:	Jung Eun Choi, Jung Hyun Kwon, Jung-Hee Kim, Wonhee Hur, Pil Soo Sung, Sang Wook Choi, Seung Kew Yoon
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4370512?pdf=render

Similar Items

microRNA-99a Restricts Replication of Hepatitis C Virus by Targeting mTOR and De Novo Lipogenesis
by: Eun Byul Lee, et al.
Published: (2020-06-01)

Anti-fibrotic effects of branched-chain amino acids on hepatic stellate cells
by: Hae Lim Lee, et al.
Published: (2022-01-01)

Aronia melanocarpa Extract Ameliorates Hepatic Lipid Metabolism through PPARγ2 Downregulation.
by: Chung-Hwa Park, et al.
Published: (2017-01-01)

Serine Protease HtrA2/Omi Deficiency Impairs Mitochondrial Homeostasis and Promotes Hepatic Fibrogenesis via Activation of Hepatic Stellate Cells
by: Wonhee Hur, et al.
Published: (2019-09-01)

Solitary fibrous tumor of the liver mimicking malignancy
by: Hee Chul Nam, et al.
Published: (2020-05-01)

Molecular Pathogenesis of Radiation-Induced Cell Toxicity in Stem Cells
by: Wonhee Hur, et al.
Published: (2017-12-01)

Tenofovir disoproxil fumarate directly ameliorates liver fibrosis by inducing hepatic stellate cell apoptosis via downregulation of PI3K/Akt/mTOR signaling pathway.
by: Sung Won Lee, et al.
Published: (2021-01-01)

Tenofovir disoproxil fumarate directly ameliorates liver fibrosis by inducing hepatic stellate cell apoptosis via downregulation of PI3K/Akt/mTOR signaling pathway
by: Sung Won Lee, et al.
Published: (2021-01-01)

MiR-23b-3p suppresses epithelial-mesenchymal transition, migration, and invasion of hepatocellular carcinoma cells by targeting c-MET
by: Na Ri Park, et al.
Published: (2022-10-01)

Branched-chain amino acids ameliorate fibrosis and suppress tumor growth in a rat model of hepatocellular carcinoma with liver cirrhosis.
by: Jung Hoon Cha, et al.
Published: (2013-01-01)

Structural Insight into the Critical Role of the N-Terminal Region in the Catalytic Activity of Dual-Specificity Phosphatase 26.
by: Eun-Young Won, et al.
Published: (2016-01-01)

A Case of Ulcerative Colitis Following Acute Hepatitis Induced by Epstein-Barr Virus Infection
by: Seung Hyun Oh, et al.
Published: (2016-08-01)

Factors associated with the survival outcomes of patients with untreated hepatocellular carcinoma: An analysis of nationwide data
by: Min Jung Kwon, et al.
Published: (2023-03-01)

Preoperative Serum Alkaline Phosphatase and Neurological Outcome of Cerebrovascular Surgery
by: Seongjoo Park, et al.
Published: (2022-05-01)

Interferon-free treatment for hepatitis C virus infection induces normalization of extrahepatic type I interferon signaling
by: Pil Soo Sung, et al.
Published: (2018-09-01)

Diffusion-Weighted Magnetic Resonance Imaging in Hepatocellular Carcinoma as a Predictor of a Response to Cisplatin-Based Hepatic Arterial Infusion Chemotherapy
by: Pil Soo Sung, et al.
Published: (2020-11-01)

Noninvasive predictors of nonalcoholic steatohepatitis in Korean patients with histologically proven nonalcoholic fatty liver disease
by: Young Seok Kim, et al.
Published: (2013-06-01)

Persistence of intrahepatic hepatitis B virus DNA integration in patients developing hepatocellular carcinoma after hepatitis B surface antigen seroclearance
by: Jeong Won Jang, et al.
Published: (2021-01-01)

Management of Intramural Esophageal Dissection with Gastric Feeding Tube in an Alcoholic-hepatitis Patient
by: Ryoung Eun Ko, et al.
Published: (2016-01-01)

The small molecule kobusone can stimulate islet β-cell replication
by: Jin woo Choi, et al.
Published: (2021-07-01)

Effects of Positive Hepatitis B Core Antibody and Metabolic Disorders in Hepatocellular Carcinoma in an Endemic Area of Hepatitis B Virus
by: Hae Lim Lee, et al.
Published: (2021-08-01)

Comparative Analysis of Lenvatinib and Hepatic Arterial Infusion Chemotherapy in Unresectable Hepatocellular Carcinoma: A Multi-Center, Propensity Score Study
by: Jaejun Lee, et al.
Published: (2021-09-01)

Protein tyrosine phosphatase profiling studies during brown adipogenic differentiation of mouse primary brown preadipocytes
by: Won Kon Kim, et al.
Published: (2013-11-01)

<i>Levilactobacillus brevis</i> MG5311 Alleviates Ethanol-Induced Liver Injury by Suppressing Hepatic Oxidative Stress in C57BL/6 Mice
by: Hyunna Jung, et al.
Published: (2022-12-01)

Blood-based biomarkers for immune-based therapy in advanced HCC: Promising but a long way to go
by: Pil Soo Sung, et al.
Published: (2022-10-01)

Reactivation of hepatitis B virus in HBsAg-negative patients with hepatocellular carcinoma.
by: Jeong Won Jang, et al.
Published: (2015-01-01)

Whole blood viscosity is associated with extrahepatic metastases and survival in patients with hepatocellular carcinoma.
by: Ji Won Han, et al.
Published: (2021-01-01)

Cold-Water Immersion Promotes Antioxidant Enzyme Activation in Elite Taekwondo Athletes
by: Eun-Hee Park, et al.
Published: (2021-03-01)

P27 Protects Neurons from Ischemic Damage by Suppressing Oxidative Stress and Increasing Autophagy in the Hippocampus
by: Woosuk Kim, et al.
Published: (2020-12-01)

An Immunological Perspective on the Mechanism of Drug Induced Liver Injury: Focused on Drugs for Treatment of Hepatocellular Carcinoma and Liver Transplantation
by: Soon Kyu Lee, et al.
Published: (2023-03-01)

Burst Suppression Patterns on an Electroencephalogram of an Infant with Congenital Central Hypoventilation
by: Eun Hye Lee, et al.
Published: (2016-08-01)

Safety and effectiveness of direct-acting antivirals in patients with chronic hepatitis C and chronic kidney disease
by: Ji Eun Ryu, et al.
Published: (2022-09-01)

Interleukin-13 receptor alpha 2 expression in tumor cells is associated with reduced disease-free survival in patients with luminal subtype invasive breast cancer
by: Hee Jung Kwon, et al.
Published: (2018-06-01)

Comparative Analysis of Atezolizumab Plus Bevacizumab and Hepatic Artery Infusion Chemotherapy in Unresectable Hepatocellular Carcinoma: A Multicenter, Propensity Score Study
by: Ji Hoon Kim, et al.
Published: (2023-08-01)

Experimental and Computational Study to Reveal the Potential of Non-Polar Constituents from <i>Hizikia fusiformis</i> as Dual Protein Tyrosine Phosphatase 1B and α-Glucosidase Inhibitors
by: Su Hui Seong, et al.
Published: (2019-05-01)

Death-Associated Protein 6 (Daxx) Alleviates Liver Fibrosis by Modulating Smad2 Acetylation
by: Sung-Min Kim, et al.
Published: (2021-07-01)

Impact of Lifestyle Diseases on Postoperative Complications and Survival in Elderly Patients with Stage I Non-Small Cell Lung Cancer
by: Sang Seok Jeong, et al.
Published: (2017-04-01)

The Challenging and Transformative Implications of Education for Sustainable Development: A Case Study in South Korea
by: Jung Hee Sung, et al.
Published: (2022-04-01)

Exosomal miR-125b Exerts Anti-Metastatic Properties and Predicts Early Metastasis of Hepatocellular Carcinoma
by: Hye Seon Kim, et al.
Published: (2021-07-01)

Exploring Cardiac Exosomal RNAs of Acute Myocardial Infarction
by: Seung Eun Jung, et al.
Published: (2024-02-01)