Exercise activates Sirt1-mediated Drp1 acetylation and inhibits hepatocyte apoptosis to improve nonalcoholic fatty liver disease

Exercise activates Sirt1-mediated Drp1 acetylation and inhibits hepatocyte apoptosis to improve nonalcoholic fatty liver disease

Abstract Purpose Aerobic exercise has shown beneficial effects in the prevention and treatment of non-alcoholic fatty liver disease (NAFLD). Nevertheless, the regulatory mechanism is not turely clear. Therefore, we aim to clarify the possible mechanism by investigating the effects of aerobic exercis...

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Bibliographic Details
Main Authors: Zongqiang Hu, Hongyu Zhang, Yiting Wang, Boyi Li, Kaiyu Liu, Jianghua Ran, Li Li
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Lipids in Health and Disease
Subjects:
NAFLD
Aerobic exercise
Srit1
Drp1 acetylation
Mitochondrial dysfunction
Online Access:https://doi.org/10.1186/s12944-023-01798-z

Internet

https://doi.org/10.1186/s12944-023-01798-z

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