NRF2 Enables EGFR Signaling in Melanoma Cells

Receptor tyrosine kinases (RTK) are rarely mutated in cutaneous melanoma, but the expression and activation of several RTK family members are associated with a proinvasive phenotype and therapy resistance. Epidermal growth factor receptor (EGFR) is a member of the RTK family and is only expressed in...

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Bibliographic Details
Main Authors: Julia Katharina Charlotte Kreß, Christina Jessen, André Marquardt, Anita Hufnagel, Svenja Meierjohann
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/8/3803