Force-Bioreactor for Assessing Pharmacological Therapies for Mechanobiological Targets

Tissue fibrosis is a major health issue that impacts millions of people and is costly to treat. However, few effective anti-fibrotic treatments are available. Due to their central role in fibrotic tissue deposition, fibroblasts and myofibroblasts are the target of many therapeutic strategies centere...

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Bibliographic Details
Main Authors: Austin J. Scholp, Jordan Jensen, Sathivel Chinnathambi, Keerthi Atluri, Alyssa Mendenhall, Timothy Fowler, Aliasger K. Salem, James A. Martin, Edward A. Sander
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.907611/full