Metabolism‐Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53‐Mutant Colon Cancer

Metabolism‐Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53‐Mutant Colon Cancer

Abstract Although targeting cancer metabolism is a promising therapeutic strategy, clinical success depends on accurate molecular and metabolic subtyping. Here, this study reports two metabolism‐based molecular subtypes associated with the ketogenic treatment of colon cancer: glycolytic (glycolysis+...

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Bibliographic Details
Main Authors: Meng Tang, Hui Xu, Hongyan Huang, Hao Kuang, Chenxi Wang, Qinqin Li, Xin Zhang, Yizhong Ge, Mengmeng Song, Xi Zhang, Ziwen Wang, Chaobing Ma, Jinlin Kang, Wanfang Zhang, You Wang, Bo Zhang, Xiaowei Zhang, Yongbing Chen, Minghua Cong, Gerry Melino, Xiaobin Wang, Fuxiang Zhou, Qiang Sun, Hanping Shi
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Advanced Science
Subjects:
colon cancer
ketogenic therapy
metabolic subtype
OXCT1
p53
Online Access:https://doi.org/10.1002/advs.202201992

Internet

https://doi.org/10.1002/advs.202201992

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