High-fat, high-carbohydrate diet-induced prediabetes preconception in Sprague–Dawley rats as a risk factor for the development of preeclampsia: assessing changes in placental metabolic insults

High-fat, high-carbohydrate diet-induced prediabetes preconception in Sprague–Dawley rats as a risk factor for the development of preeclampsia: assessing changes in placental metabolic insults

IntroductionHyperglycemia preconception deranges the establishment of a functional placenta; however, the risk of developing preeclampsia (PE) in prediabetic patients remains obscure. The aim was to assess abnormal placental changes as a risk factor for the development of PE in high-fat, high-carboh...

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Bibliographic Details
Main Authors: Asiphaphola Ludidi, Anelisiwe Siboto, Ayanda Nkosi, Nombuso Duduzile Xulu, Andile Khathi, Ntethelelo Hopewell Sibiya, Phikelelani Siphosethu Ngubane
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Nutrition
Subjects:
hyperglycemia
diet
inflammation
placenta
prediabetes
preeclampsia
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2023.1241785/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2023.1241785/full

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