Peptide-based approaches to directly target alpha-synuclein in Parkinson’s disease
Abstract Peptides and their mimetics are increasingly recognised as drug-like molecules, particularly for intracellular protein-protein interactions too large for inhibition by small molecules, and inaccessible to larger biologics. In the past two decades, evidence associating the misfolding and agg...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-11-01
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Series: | Molecular Neurodegeneration |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13024-023-00675-8 |