Peptide-based approaches to directly target alpha-synuclein in Parkinson’s disease

Abstract Peptides and their mimetics are increasingly recognised as drug-like molecules, particularly for intracellular protein-protein interactions too large for inhibition by small molecules, and inaccessible to larger biologics. In the past two decades, evidence associating the misfolding and agg...

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Bibliographic Details
Main Authors: Scott G. Allen, Richard M. Meade, Lucy L. White Stenner, Jody M. Mason
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Molecular Neurodegeneration
Subjects:
Online Access:https://doi.org/10.1186/s13024-023-00675-8