Blood Bacterial DNA Load and Profiling Differ in Colorectal Cancer Patients Compared to Tumor-Free Controls

Blood Bacterial DNA Load and Profiling Differ in Colorectal Cancer Patients Compared to Tumor-Free Controls

Inflammation and immunity are linked to intestinal adenoma (IA) and colorectal cancer (CRC) development. The gut microbiota is associated with CRC risk. Epithelial barrier dysfunction can occur, possibly leading to increased intestinal permeability in CRC patients. We conducted a case-control study...

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Bibliographic Details
Main Authors: Massimiliano Mutignani, Roberto Penagini, Giorgio Gargari, Simone Guglielmetti, Marcello Cintolo, Aldo Airoldi, Pierfrancesco Leone, Pietro Carnevali, Clorinda Ciafardini, Giulio Petrocelli, Federica Mascaretti, Barbara Oreggia, Lorenzo Dioscoridi, Federica Cavalcoli, Massimo Primignani, Francesco Pugliese, Paola Bertuccio, Pietro Soru, Carmelo Magistro, Giovanni Ferrari, Michela C. Speciani, Giulia Bonato, Marta Bini, Paolo Cantù, Flavio Caprioli, Marcello Vangeli, Edoardo Forti, Stefano Mazza, Giulia Tosetti, Rossella Bonzi, Maurizio Vecchi, Carlo La Vecchia, Marta Rossi
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
bacterial translocation
bacterial 16S rRNA gene
case-control study
colon cancer diagnoses
microbiome
Online Access:https://www.mdpi.com/2072-6694/13/24/6363

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https://www.mdpi.com/2072-6694/13/24/6363

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