NKCC1 and KCC2 Chloride Transporters Have Different Membrane Dynamics on the Surface of Hippocampal Neurons

Na-K-2Cl cotransporter 1 (NKCC1) regulates chloride influx in neurons and thereby GABA<sub>A</sub> receptor activity in normal and pathological conditions. Here, we characterized in hippocampal neurons the membrane expression, distribution and dynamics of exogenous NKCC1a and NKCC1b isof...

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Bibliographic Details
Main Authors: Erwan Pol, Etienne Côme, Zaha Merlaud, Juliette Gouhier, Marion Russeau, Sophie Scotto-Lomassese, Imane Moutkine, Xavier Marques, Sabine Lévi
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/19/2363