Nano-Pulse Treatment Overcomes the Immunosuppressive Tumor Microenvironment to Elicit In Situ Vaccination Protection against Breast Cancer

Nano-Pulse Treatment Overcomes the Immunosuppressive Tumor Microenvironment to Elicit In Situ Vaccination Protection against Breast Cancer

We previously reported that nano-pulse treatment (NPT), a pulsed power technology, resulted in 4T1-luc mammary tumor elimination and a strong in situ vaccination, thereby completely protecting tumor-free animals against a second live tumor challenge. The mechanism whereby NPT mounts effective antitu...

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Bibliographic Details
Main Authors: Anthony Nanajian, Megan Scott, Niculina I. Burcus, Brittney L. Ruedlinger, Edwin A. Oshin, Stephen J. Beebe, Siqi Guo
Format: Article
Language:English
Published: MDPI AG 2024-06-01
Series:Vaccines
Subjects:
nano-pulse treatment (NPT)
in situ vaccination
breast cancer
tumor microenvironment
immunosuppression
apoptosis
Online Access:https://www.mdpi.com/2076-393X/12/6/633

Internet

https://www.mdpi.com/2076-393X/12/6/633

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