UBE2J1 knockdown promotes cell apoptosis in endometrial cancer via regulating PI3K/AKT and MDM2/p53 signaling

UBE2J1 knockdown promotes cell apoptosis in endometrial cancer via regulating PI3K/AKT and MDM2/p53 signaling

Emerging evidence has demonstrated that ubiquitin conjugating enzyme E2 J1 (UBE2J1) exerts pivotal function in many cancers. UBE2J1 was reported to be dysregulated in endometrial cancer (EC). This study was designed to further investigate the regulatory character and mechanism of UBE2J1 in EC. Bioin...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhang Ping, Guo Huiping, Zhao Fang, Jia Ke, Yang Fei, Liu Xiaoli
Materialtyp: Artikel
Språk:English
Publicerad: De Gruyter 2023-02-01
Serie:Open Medicine
Ämnen:
cell apoptosis
endometrial cancer
mdm2/p53 pathway
pi3k/akt pathway
ube2j1
Länkar:https://doi.org/10.1515/med-2022-0567

Internet

https://doi.org/10.1515/med-2022-0567

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