Melatonin and Its Metabolites Can Serve as Agonists on the Aryl Hydrocarbon Receptor and Peroxisome Proliferator-Activated Receptor Gamma

Melatonin and Its Metabolites Can Serve as Agonists on the Aryl Hydrocarbon Receptor and Peroxisome Proliferator-Activated Receptor Gamma

Melatonin is widely present in Nature. It has pleiotropic activities, in part mediated by interactions with high-affinity G-protein-coupled melatonin type 1 and 2 (MT1 and MT2) receptors or under extreme conditions, e.g., ischemia/reperfusion. In pharmacological concentrations, it is given to counte...

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Bibliographic Details
Main Authors: Andrzej T. Slominski, Tae-Kang Kim, Radomir M. Slominski, Yuwei Song, Shariq Qayyum, Wojciech Placha, Zorica Janjetovic, Konrad Kleszczyński, Venkatram Atigadda, Yuhua Song, Chander Raman, Cornelis J. Elferink, Judith Varady Hobrath, Anton M. Jetten, Russel J. Reiter
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
melatonin
melatonin metabolites
AhR
PPARγ
receptors
modeling
Online Access:https://www.mdpi.com/1422-0067/24/20/15496

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https://www.mdpi.com/1422-0067/24/20/15496

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