Dynamic Neuroimmune Profile during Mid-life Aging in the Female Brain and Implications for Alzheimer Risk

Summary: Aging and endocrine transition states can significantly impact inflammation across organ systems. Neuroinflammation is well documented in Alzheimer disease (AD). Herein, we investigated neuroinflammation that emerges during mid-life aging, chronological and endocrinological, in the female b...

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Bibliographic Details
Main Authors: Aarti Mishra, Yuan Shang, Yiwei Wang, Eliza R. Bacon, Fei Yin, Roberta D. Brinton
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220310269