High-throughput analysis of ANRIL circRNA isoforms in human pancreatic islets

Abstract The antisense non-coding RNA in the INK locus (ANRIL) is a hotspot for genetic variants associated with cardiometabolic disease. We recently found increased ANRIL abundance in human pancreatic islets from donors with certain Type II Diabetes (T2D) risk-SNPs, including a T2D risk-SNP located...

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Bibliographic Details
Main Authors: Hannah J. MacMillan, Yahui Kong, Ezequiel Calvo-Roitberg, Laura C. Alonso, Athma A. Pai
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-11668-w