The critical role of Toll-like receptor-mediated signaling in cancer immunotherapy

The critical role of Toll-like receptor-mediated signaling in cancer immunotherapy

Toll-like receptors (TLR) play a dual regulatory role in the tumor microenvironment (TME). TLR agonists (TLRa) elicit both innate and adaptive immune responses to achieve anti-tumor effects, whereas the inflammatory response induced by TLRa contributes to the immune escape of tumor cells. Preliminar...

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Bibliographic Details
Main Authors: Xue Chen, Yunxiao Zhang, Yao Fu
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Medicine in Drug Discovery
Subjects:
Toll-like receptor
Agonist
Antagonist
Cancer immunotherapy
Tumor microenvironment
Online Access:http://www.sciencedirect.com/science/article/pii/S2590098622000033

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http://www.sciencedirect.com/science/article/pii/S2590098622000033

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