The converging roles of Batten disease proteins in neurodegeneration and cancer

Summary: Epidemiological studies have reported an inverse correlation between cancer and neurodegenerative disorders, and increasing evidence shows that similar genes and pathways are dysregulated in both diseases but in a contrasting manner. Given the genetic convergence of the neuronal ceroid lipo...

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Bibliographic Details
Main Authors: Shyong Quan Yap, Sabateeshan Mathavarajah, Robert Joseph Huber
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221003059