The Fgf/Erf/NCoR1/2 repressive axis controls trophoblast cell fate

Abstract Placental development relies on coordinated cell fate decisions governed by signalling inputs. However, little is known about how signalling cues are transformed into repressive mechanisms triggering lineage-specific transcriptional signatures. Here, we demonstrate that upon inhibition of t...

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Bibliographic Details
Main Authors: Andreas Lackner, Michael Müller, Magdalena Gamperl, Delyana Stoeva, Olivia Langmann, Henrieta Papuchova, Elisabeth Roitinger, Gerhard Dürnberger, Richard Imre, Karl Mechtler, Paulina A. Latos
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38101-8