Synthesis and Antimycobacterial Evaluation of <i>N</i>-(4-(Benzyloxy)benzyl)-4-aminoquinolines

Synthesis and Antimycobacterial Evaluation of <i>N</i>-(4-(Benzyloxy)benzyl)-4-aminoquinolines

Tuberculosis remains a global health problem that affects millions of people around the world. Despite recent efforts in drug development, new alternatives are required. Herein, a series of 27 <i>N</i>-(4-(benzyloxy)benzyl)-4-aminoquinolines were synthesized and evaluated for their abili...

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Bibliographic Details
Main Authors: Estevão Silveira Grams, Alessandro Silva Ramos, Mauro Neves Muniz, Raoní S. Rambo, Marcia Alberton Perelló, Nathalia Sperotto, Laura Calle González, Lovaine Silva Duarte, Luiza Galina, Adilio Silva Dadda, Guilherme Arraché Gonçalves, Cristiano Valim Bizarro, Luiz Augusto Basso, Pablo Machado
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
<i>Mycobacterium tuberculosis</i>
drug discovery
synthesis
quinolines
tuberculosis
Online Access:https://www.mdpi.com/1420-3049/27/8/2556

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https://www.mdpi.com/1420-3049/27/8/2556

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