The Antiviral Apparatus: STING and Oncolytic Virus Restriction

A network of pattern recognition receptors (PRRs) is responsible for the detection of invading viruses and acts as the trigger for the host antiviral response. Central to this apparatus is stimulator of interferon genes (STING), which functions as a node and integrator of detection signals. Owing to...

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Bibliographic Details
Main Authors: Joel Lee, Mohammed G. Ghonime, Ruoning Wang, Kevin A. Cassady
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770519300117