Binding of Citrate-Fe<sup>3+</sup> to Plastic Culture Dishes, an Artefact Useful as a Simple Technique to Screen for New Iron Chelators

Binding of Citrate-Fe<sup>3+</sup> to Plastic Culture Dishes, an Artefact Useful as a Simple Technique to Screen for New Iron Chelators

NaCT mediates citrate uptake in the liver cell line HepG2. When these cells were exposed to iron (Fe<sup>3+</sup>), citrate uptake/binding as monitored by the association of [<sup>14</sup>C]-citrate with cells increased. However, there was no change in NaCT expression and fun...

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Bibliographic Details
Main Authors: Jiro Ogura, Toshihiro Sato, Kei Higuchi, Sathish Sivaprakasam, Jonathan Kopel, Yangzom D. Bhutia, Vadivel Ganapathy
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
citrate-Fe<sup>3+</sup> chelate
iron chelators
deferiprone
deferoxamine
2,3-dihydroxybenzoic acid
2,5-dihydroxybenzoic acid
Online Access:https://www.mdpi.com/1422-0067/23/12/6657

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https://www.mdpi.com/1422-0067/23/12/6657

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