Identification of CYFIP2 Arg87Cys Ligands via In Silico and In Vitro Approaches

Identification of CYFIP2 Arg87Cys Ligands via In Silico and In Vitro Approaches

The advancement of next-generation sequencing has enabled the identification of specific mutations associated with early infantile epileptic encephalopathies (EIEEs). In EIEE, epileptic spasms and seizures that occur since early childhood lead to impaired neurological development. The CYFIP2 p.Arg87...

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Bibliographic Details
Main Authors: Ísis Venturi Biembengut, Emanuella de Castro Andreassa, Tatiana A. C. B. de Souza
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Biomedicines
Subjects:
CYFIP2
early infantile epileptic encephalopathies
molecular docking
drug repurposing
Online Access:https://www.mdpi.com/2227-9059/12/3/479

Internet

https://www.mdpi.com/2227-9059/12/3/479

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