METTL3 and STAT3 form a positive feedback loop to promote cell metastasis in hepatocellular carcinoma

METTL3 and STAT3 form a positive feedback loop to promote cell metastasis in hepatocellular carcinoma

Abstract Background It is well-established that most Hepatocellular carcinoma (HCC) patients die of metastasis, yet the potential mechanisms orchestrating metastasis remain poorly understood. Current evidence suggests that the dysregulation of METTL3-mediated m6A methylation modification is closely...

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Bibliographic Details
Main Authors: Bowen Liu, Jinling Cao, Biting Wu, Kaixuan Hao, Xiangyun Wang, Xin Chen, Zhifa Shen
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Cell Communication and Signaling
Subjects:
Hepatocellular carcinoma
m6A methylation modification
METTL3
STAT3
Metastasis
Online Access:https://doi.org/10.1186/s12964-023-01148-7

Internet

https://doi.org/10.1186/s12964-023-01148-7

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