CD34 Antigen and the MPL Receptor Expression Defines a Novel Class of Human Cord Blood-Derived Primitive Hematopoietic Stem Cells

In the murine hematopoietic stem cell (HSC) compartment, thrombopoietin (THPO)/MPL (THPO receptor) signaling plays an important role in the maintenance of adult quiescent HSCs. However, the role of THPO/MPL signaling in the human primitive HSC compartment has not yet been elucidated. We have identif...

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Bibliographic Details
Main Authors: Yoshikazu Matsuoka, Masaya Takahashi, Keisuke Sumide, Hiroshi Kawamura, Ryusuke Nakatsuka, Tatsuya Fujioka, Yoshiaki Sonoda M.D., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2017-06-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368916X694201