A prospective study of dietary and supplemental zinc intake and risk of type 2 diabetes depending on genetic variation in SLC30A8

A prospective study of dietary and supplemental zinc intake and risk of type 2 diabetes depending on genetic variation in SLC30A8

Abstract Background The solute carrier family 30 member 8 gene (SLC30A8) encodes a zinc transporter in the pancreatic beta cells and the major C-allele of a missense variant (rs13266634; C/T; R325W) in SLC30A8 is associated with an increased risk of type 2 diabetes (T2D). We hypothesized that the as...

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Bibliographic Details
Main Authors: Isabel Drake, George Hindy, Ulrika Ericson, Marju Orho-Melander
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Genes & Nutrition
Subjects:
Gene-nutrient interaction, Zinc, Solute carrier family 30 member 8 gene, Single nucleotide polymorphism, Cohort, Body mass index
Online Access:http://link.springer.com/article/10.1186/s12263-017-0586-y

Internet

http://link.springer.com/article/10.1186/s12263-017-0586-y

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