SARS-CoV-2 Accessory Protein ORF8 Decreases Antibody-Dependent Cellular Cytotoxicity

SARS-CoV-2 Accessory Protein ORF8 Decreases Antibody-Dependent Cellular Cytotoxicity

Viruses use many different strategies to evade host immune responses. In the case of SARS-CoV-2, its Spike mutates rapidly to escape from neutralizing antibodies. In addition to this strategy, ORF8, a small accessory protein encoded by SARS-CoV-2, helps immune evasion by reducing the susceptibility...

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Bibliographic Details
Main Authors: Guillaume Beaudoin-Bussières, Ariana Arduini, Catherine Bourassa, Halima Medjahed, Gabrielle Gendron-Lepage, Jonathan Richard, Qinghua Pan, Zhen Wang, Chen Liang, Andrés Finzi
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Viruses
Subjects:
coronavirus
SARS-CoV-2
ORF8
accessory protein
Fc-mediated effector function
ADCC
Online Access:https://www.mdpi.com/1999-4915/14/6/1237

Internet

https://www.mdpi.com/1999-4915/14/6/1237

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