Plumbagin: A Promising In Vivo Antiparasitic Candidate against <i>Schistosoma mansoni</i> and In Silico Pharmacokinetic Properties (ADMET)

Plumbagin: A Promising In Vivo Antiparasitic Candidate against <i>Schistosoma mansoni</i> and In Silico Pharmacokinetic Properties (ADMET)

Schistosomiasis, a potentially fatal chronic disease whose etiological agents are blood trematode worms of the genus <i>Schistosoma</i> spp., is one of the most prevalent and debilitating neglected diseases. The treatment of schistosomiasis depends exclusively on praziquantel (PZQ), a dr...

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Bibliographic Details
Main Authors: Lucas M. N. Silva, Wilza W. M. França, Victor H. B. Santos, Renan A. F. Souza, Adriana M. Silva, Emily G. M. Diniz, Thierry W. A. Aguiar, João V. R. Rocha, Mary A. A. Souza, Wheverton R. C. Nascimento, Reginaldo G. Lima Neto, Iranildo J. Cruz Filho, Eulália C. P. A. Ximenes, Hallysson D. A. Araújo, André L. Aires, Mônica C. P. A. Albuquerque
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biomedicines
Subjects:
naphthoquinone
plumbagin
schistosomicidal
in vivo assay <i>Schistosoma mansoni</i>
histopathology
Online Access:https://www.mdpi.com/2227-9059/11/9/2340

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https://www.mdpi.com/2227-9059/11/9/2340

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