GPR52 regulates cAMP in T cells but is dispensable for encephalitogenic responses
G-protein coupled receptors (GPCR) regulate 3’,5’-cyclic adenosine monophosphate (cAMP) levels in T cells. cAMP as ubiquitous second messenger is crucial for adequate physiology of T cells by mediating effector T cell (Teff) function as well as regulatory T cell (Treg)-mediated immunosuppression. Se...
| Հիմնական հեղինակներ: | , , , , , , , |
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| Ձևաչափ: | Հոդված |
| Լեզու: | English |
| Հրապարակվել է: |
Frontiers Media S.A.
2023-01-01
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| Շարք: | Frontiers in Immunology |
| Խորագրեր: | |
| Առցանց հասանելիություն: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.1113348/full |