Implications of dimeric activation of PDE6 for rod phototransduction

We examine the implications of a recent report providing evidence that two transducins must bind to the rod phosphodiesterase to elicit significant hydrolytic activity. To predict the rod photoreceptor's electrical response, we use numerical simulation of the two-dimensional diffusional contact...

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Bibliographic Details
Main Authors: Trevor D. Lamb, Martin Heck, Timothy W. Kraft
Format: Article
Language:English
Published: The Royal Society 2018-08-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.180076