Tumor-specific intracellular delivery: peptide-guided transport of a catalytic toxin

Peptide modification is used to optimize the transport of saporin specifically to cancer cells in vitro and in vivo, where it exerts anti-cancer actions.

Bibliographic Details
Main Authors: Curtis A. Allred, Claire Gormley, Indu Venugopal, Shunzi Li, Michael J. McGuire, Kathlynn C. Brown
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-04385-7