SparsePro: An efficient fine-mapping method integrating summary statistics and functional annotations.

Identifying causal variants from genome-wide association studies (GWAS) is challenging due to widespread linkage disequilibrium (LD) and the possible existence of multiple causal variants in the same genomic locus. Functional annotations of the genome may help to prioritize variants that are biologi...

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Bibliographic Details
Main Authors: Wenmin Zhang, Hamed Najafabadi, Yue Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-12-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011104&type=printable