Efficacy of inverso isomer of CendR peptide on tumor tissue penetration

The dense extracellular matrix and high interstitial fluid pressure of tumor tissues prevent the ability of anti-tumor agents to penetrate deep into the tumor parenchyma for treatment effects. C-end rule (CendR) peptides can enhance the permeability of tumor blood vessels and tumor tissues via bindi...

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Bibliographic Details
Main Authors: Ruifeng Wang, Qing Shen, Xue Li, Cao Xie, Weiyue Lu, Songli Wang, Jing Wang, Dongli Wang, Min Liu
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Acta Pharmaceutica Sinica B
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383517306056