Metformin modulates mitochondrial function and mitophagy in peripheral blood mononuclear cells from type 2 diabetic patients

Metformin modulates mitochondrial function and mitophagy in peripheral blood mononuclear cells from type 2 diabetic patients

Type 2 diabetes is a chronic metabolic disease that affects mitochondrial function. In this context, the rescue mechanisms of mitochondrial health, such as mitophagy and mitochondrial biogenesis, are of crucial importance. The gold standard for the treatment of type 2 diabetes is metformin, which ha...

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Bibliographic Details
Main Authors: Aranzazu M. de Marañón, Pedro Díaz-Pozo, Francisco Canet, Noelia Díaz-Morales, Zaida Abad-Jiménez, Sandra López-Domènech, Teresa Vezza, Nadezda Apostolova, Carlos Morillas, Milagros Rocha, Víctor M. Víctor
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Redox Biology
Subjects:
Metformin
Mitochondria
Mitophagy
Type 2 diabetes
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722001148

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http://www.sciencedirect.com/science/article/pii/S2213231722001148

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