Y6, an Epigallocatechin Gallate Derivative, Reverses ABCG2-Mediated Mitoxantrone Resistance

Multidrug resistance is reported to be related to the transmembrane transportation of chemotherapeutic drugs by adenosine triphosphate-binding cassette (ABC) transporters. ABC subfamily G member 2 (ABCG2) is a member of the ABC transporter superfamily proteins, which have been implicated as a key co...

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Bibliographic Details
Main Authors: Rui-Qiang Zhao, Yan Wen, Pranav Gupta, Zi-Ning Lei, Chao-Yun Cai, Gang Liang, Dong-Hua Yang, Zhe-Sheng Chen, Yu-An Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01545/full