Mitochondrial genomic analysis of late onset Alzheimer's disease reveals protective haplogroups H6A1A/H6A1B: the Cache County Study on Memory in Aging.

Mitochondrial genomic analysis of late onset Alzheimer's disease reveals protective haplogroups H6A1A/H6A1B: the Cache County Study on Memory in Aging.

Alzheimer's disease (AD) is the most common cause of dementia and AD risk clusters within families. Part of the familial aggregation of AD is accounted for by excess maternal vs. paternal inheritance, a pattern consistent with mitochondrial inheritance. The role of specific mitochondrial DNA (m...

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Bibliographic Details
Main Authors: Perry G Ridge, Taylor J Maxwell, Christopher D Corcoran, Maria C Norton, Joann T Tschanz, Elizabeth O'Brien, Richard A Kerber, Richard M Cawthon, Ronald G Munger, John S K Kauwe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3444479?pdf=render

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http://europepmc.org/articles/PMC3444479?pdf=render

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