Investigation of the Rv3065, Rv2942, Rv1258c, Rv1410c, and Rv2459 efflux pump genes expression among multidrug-resistant Mycobacterium tuberculosis clinical isolates

Investigation of the Rv3065, Rv2942, Rv1258c, Rv1410c, and Rv2459 efflux pump genes expression among multidrug-resistant Mycobacterium tuberculosis clinical isolates

Background: Different resistance mechanisms for multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) have been reported. Although mutations in target genes are the main cause of drug resistance, efflux pumps (Eps) also play an important role in this process....

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Bibliographic Details
Main Authors: Fatemeh Shahi, Azar Dokht Khosravi, Mohammad Reza Tabandeh, Shokrollah Salmanzadeh
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Heliyon
Subjects:
Efflux pumps
MDR-TB
Mutation
Tuberculosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021016698

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http://www.sciencedirect.com/science/article/pii/S2405844021016698

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