High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL-17 against M. tuberculosis antigen

High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL-17 against M. tuberculosis antigen

BackgroundInterleukin-17–producing CD4 T cells contribute to the control of Mycobacterium tuberculosis (Mtb) infection in humans; whether infection with human immunodeficiency virus (HIV) disproportionately affects distinct Th17-cell subsets that respond to Mtb is incompletely defined.MethodsWe perf...

Full description

Bibliographic Details
Main Authors: Paul Ogongo, Anthony Tran, Florence Marzan, David Gingrich, Melissa Krone, Francesca Aweeka, Cecilia S. Lindestam Arlehamn, Jeffrey N. Martin, Steven G. Deeks, Peter W. Hunt, Joel D. Ernst
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
interleukin-17
CD4 T-cells
antigen-responsive
immunity
tuberculosis
ART-suppressed
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1378040/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1378040/full

Similar Items