Human ACE2 Genetic Polymorphism Affecting SARS-CoV and SARS-CoV-2 Entry into Cells
ABSTRACT Severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 have a single envelope glycoprotein (S protein) that binds to human angiotensin-converting enzyme 2 (ACE2) on the host cell membrane. Previous mutational scanning studies have suggested that some substitutions correspon...
Main Authors: | , , , , , , , |
---|---|
格式: | Article |
語言: | English |
出版: |
American Society for Microbiology
2022-08-01
|
叢編: | Microbiology Spectrum |
主題: | |
在線閱讀: | https://journals.asm.org/doi/10.1128/spectrum.00870-22 |