Biochemical characterization of the fidelity of poliovirus RNA-dependent RNA polymerase
<p>Abstract</p> <p>Background</p> <p>Putative high mutation rates of RNA viruses are believed to mediate undesirable phenomena, such as emergence of drug resistance. However, very little is known about biochemical fidelity rates for viral RNA-dependent RNA polymerases....
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2007-05-01
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| Series: | Virology Journal |
| Online Access: | http://www.virologyj.com/content/4/1/44 |