Therapeutic effect of demethylated hydroxylated phillygenin derivative on Helicobacter pylori infection

Therapeutic effect of demethylated hydroxylated phillygenin derivative on Helicobacter pylori infection

Modifying and transforming natural antibacterial products is a novel idea for developing new efficacious compounds. Phillygenin has an inhibitory effect on H. pylori. The aim of the present study was to prepare a phillygenin derivative (PHI-Der) through demethylation and hydroxylation. The minimum i...

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Bibliographic Details
Main Authors: Ru-Jia Li, Jia-yin Xu, Xue Wang, Li-juan Liao, Xian Wei, Ping Xie, Wen-yan Xu, Zhen-yi Xu, Shuo-hua Xie, Yu-ying Jiang, Liang Huang, Lu-yao Wang, Gan-rong Huang, Yan-Qiang Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Microbiology
Subjects:
Helicobacter pylori
phillygenin
demethyl hydroxylation
derivatives
therapeutic effect
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1071603/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1071603/full

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