Developmental, cytogenetic and epigenetic consequences of removing complex proteins and adding melatonin during in vitro maturation of bovine oocytes

Developmental, cytogenetic and epigenetic consequences of removing complex proteins and adding melatonin during in vitro maturation of bovine oocytes

BackgroundIn vitro maturation (IVM) of germinal vesicle intact oocytes prior to in vitro fertilization (IVF) is practiced widely in animals. In human assisted reproduction it is generally reserved for fertility preservation or where ovarian stimulation is contraindicated. Standard practice incorpora...

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Bibliographic Details
Main Authors: Desmond A. R. Tutt, Gizem Guven-Ates, Wing Yee Kwong, Rob Simmons, Fei Sang, Giuseppe Silvestri, Carla Canedo-Ribeiro, Alan H. Handyside, Remi Labrecque, Marc-André Sirard, Richard D. Emes, Darren K. Griffin, Kevin D. Sinclair
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Endocrinology
Subjects:
oocyte
aneuploidy
DNA methylation
IVM
serum
melatonin
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1280847/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1280847/full

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