The GTPase Rab43 Controls the Anterograde ER-Golgi Trafficking and Sorting of GPCRs

Summary: G-protein-coupled receptors (GPCRs) constitute the largest superfamily of cell-surface signaling proteins. However, mechanisms underlying their surface targeting and sorting are poorly understood. Here, we screen the Rab family of small GTPases in the surface transport of multiple GPCRs. We...

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Bibliographic Details
Main Authors: Chunman Li, Zhe Wei, Yi Fan, Wei Huang, Yunchao Su, Honglin Li, Zheng Dong, Mitsunori Fukuda, Mostafa Khater, Guangyu Wu
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717314286