The genetic basis of multiple system atrophy

The genetic basis of multiple system atrophy

Abstract Multiple system atrophy (MSA) is a heterogenous, uniformly fatal neurodegenerative ɑ-synucleinopathy. Patients present with varying degrees of dysautonomia, parkinsonism, cerebellar dysfunction, and corticospinal degeneration. The underlying pathophysiology is postulated to arise from aberr...

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Bibliographic Details
Main Authors: Fan Shuen Tseng, Joel Qi Xuan Foo, Aaron Shengting Mai, Eng-King Tan
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Translational Medicine
Subjects:
Multiple system atrophy
Neurodegeneration
Movement disorders
Genetics
Mutations
Polymorphisms
Online Access:https://doi.org/10.1186/s12967-023-03905-1

Internet

https://doi.org/10.1186/s12967-023-03905-1

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