Repurposing Amphotericin B: anti-microbial, molecular docking and molecular dynamics simulation studies suggest inhibition potential of Amphotericin B against MRSA

Abstract Amphotericin B (AMPH) is an anti-fungal drug and this study, for the first time as best of our knowledge, reports the repurposing of the Amphotericin B. The drug was found to show significant antibacterial potential revealed by antimicrobial screening, molecular docking, and mode of action...

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Bibliographic Details
Main Authors: Neha Farid, Khair Bux, Kashif Ali, Asma Bashir, Rahima Tahir
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Chemistry
Subjects:
Online Access:https://doi.org/10.1186/s13065-023-00980-9