Relevance of the NLRP3 Inflammasome in the Pathogenesis of Chronic Liver Disease

Relevance of the NLRP3 Inflammasome in the Pathogenesis of Chronic Liver Disease

Inflammation is a common characteristic of chronic liver disease (CLD). Inflammasomes are multiprotein complexes that can sense and recognize various exogenous and endogenous danger signals, eventually activating interleukin (IL)-1β and IL-18. The sensor component of the inflammasome system is a nuc...

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Bibliographic Details
Main Authors: Xiaoqin Wu, Lei Dong, Xianhe Lin, Jun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
inflammasome
inflammation
viral hepatitis
non-alcoholic steatohepatitis
alcoholic liver disease
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01728/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01728/full

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